Chalcone Derivatives: Role in Anticancer Therapy
نویسندگان
چکیده
منابع مشابه
Synthesis and anticancer activity assay of novel chalcone sulfonamide derivatives
Chalcones, or 1,3–diaryl–2–propen–1–ones, one of the major classes of natural products and posses many useful properties like anticancer, antibacterial, antifungal, anti–inflammatory, antimalarial and anti–diabetic activity. We report in this communication the synthesis and anticancer study of a number of novel chalcone sulfonamides. Our results indicate that the synthesis of chalcone sulfonami...
متن کاملSynthesis and anticancer activity assay of novel chalcone sulfonamide derivatives
Chalcones, or 1,3–diaryl–2–propen–1–ones, one of the major classes of natural products and posses many useful properties like anticancer, antibacterial, antifungal, anti–inflammatory, antimalarial and anti–diabetic activity. We report in this communication the synthesis and anticancer study of a number of novel chalcone sulfonamides. Our results indicate that the synthesis of chalcone sulfonami...
متن کاملSynthesis and Anticancer Activity Assay of Novel Chalcone-Sulfonamide Derivatives
Today Cancer remains to be one of the most deadly diseases in the world. Due to the potential anticancer activity of the chalcone and sulfonamide moieties, five novel hybrid compounds containing both structures have been designed and synthesized in 3 steps. The synthesized compounds were established on the basis of IR, 1H NMR, 13C NMR spectral data, and elemental analysis and also they were scr...
متن کاملSynthesis and In-vitro Evaluation of Copolyester- Chalcone Derivatives as Potential Anticancer Agents
A new series of copolyester chalcone derivatives were synthesised from 1, 3-bis (4-hydroxy-3methoxyphenyl) propenone (BHMPP) and 1(3, 5-dihydroxyphenyl)-3-(4-methoxyphenyl) propenone (DHPMPP) with adipoyl, suberoyl, azeloyl and sebacoyl chlorides by phase transfer catalysed polycondensation method. The microstructure of the repeating unit was confirmed by IR, 1 H and 13 C NMR. These copolyester...
متن کاملDesign and Development of Halogenated Chalcone Derivatives as Potential Anticancer Agents
Purpose: To design and develop halogenated chalcone derivatives and evaluate them as anticancer agents using different cancer cell lines. Methods: Based on in silico design and docking on known target, crystal structure of the complex of interleukin-1beta converting enzyme (ICE) with a peptide based inhibitor, (3S )-N-Methanesulfonyl-3({1-[N-(2-naphtoyl)-l-valyl]-l-prolyl}amino)-4-oxobutanamide...
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ژورنال
عنوان ژورنال: Biomolecules
سال: 2021
ISSN: 2218-273X
DOI: 10.3390/biom11060894